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2017-2020

For detail, see the link 

(Nagoya University

 Faculty Profile)

Original Papers

M. Kita, K. Yamagishi, K. Tsuchiya, Y. Seguchi, H. Nakane, and H. Kigoshi

Development of photoaffinity derivatives of the antitumor macrolide aplyronine A, a PPI-inducer between actin and tubulin. 

Bioorg. Med. Chem.  25, 6322–6331 (2017). 

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A. Murni, N. Hanif, M. Kita, and L. K. Darusman

Methyl 10-epi-pheophorbide A from MCF-7 cells active layer of the Indonesian Ficus deltoidea jack leaves.

Int. J. Pharm. Pharm. Sci.  9, 183–186 (2017). 

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A. Sakai, E. Noguchi, T. Fukushima, M. Tagawa, A. Iwabuchi, M. Kita, K. Kakisaka, A. Miyasaka, Y. Takikawa, and R. Sumazaki

Identification of amino acids in antigen-binding site of class II HLA proteins independently associated with hepatitis B vaccine response.

Vaccine  35, 703–710 (2017). 

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D. Kawashima, T. Hosoya, H. Tomoda, M. Kita, and H. Shigemori 

Sydowianumols A, B, and C, three new compounds from discomycete Poculum pseudosydowianum. 

Chem. Pharm. Bull. 66, 826–829 (2018). 

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M. Kita, S. Watanabe, H. Oka, and H. Kigoshi

Synthesis of the trisoxazole macrolactone of mycalolides via template-directed E-selective ring-closing metathesis. 

Tetrahedron Lett. 59, 3664–3668 (2018). 

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R. Watanabe, Y. Hu, K. Iio, K. Yoneda, A. Hattori, A. Arai, H. Kigoshi, and M. Kita

Specific protein-labeling and ligand-binding position analysis with amidopyrene probes as LDI MS tags. 

Org. Biomol. Chem. 16, 7883–7890 (2018). 

M. Zhang, T. Sunaba, Y. Sun, K. Sasaki, H. Isoda, H. Kigoshi, and M. Kita

Anti-inflammatory marine cyclic peptide stylissatin A and its derivatives inhibit differentiation of murine preadipocytes. 

Chem. Commun. 55, 5471–5474 (2019). 

K. Futaki, M. Takahashi, K. Tanabe, A. Fujieda, H. Kigoshi, and M. Kita

Synthesis and biological activities of aplyronine A analogs toward the development of antitumor PPI inducers between actin and tubulin: conjugation of the C1–C9 macrolactone part and the C24–C34 side-chain. 

ACS Omega 4, 8598–8613 (2019). 

J. J. Sato, T. M. Bradford, K. N. Armstrong, S. C. Donnellan, L. M. Echenique-Diaz, G. Begué-Quiala, J. Gámez-Díez, N. Yamaguchi, S. T. Nguyen, M. Kita, and S. D. Ohdachi

Post K-Pg diversification of the mammalian order Eulipotyphla as suggested by phylogenomic analyses of ultra-conserved elements. 

Mol. Phylogent. Evol. 141, 106655 (2019).

A. Arai, R. Watanabe, A. Hattori, K. Iio, Y. Hu, K. Yoneda, H. Kigoshi, and M. Kita

N,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis. 

Sci. Rep. 10, 7311 (2020). 

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M. Hirukawa, M. Zhang, L. M. Echenique–Diaz, K. Mizota, S. D. Ohdachi, G. Begué–Quiala, J. L. Delgado–Labañino, J. Gámez–Díez, J. Alvarez–Lemus, L. Galano Machado, M. Suárez Núñez, T. Shibata, H. Kigoshi, and M. Kita

Isolation and structure-activity relationship studies of jacaranones: anti-inflammatory quinoids from the Cuban endemic plant Jacaranda arborea (Bignoniaceae). 

Tetrahedron Lett. 61, 152005 (2020). 

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M. Zhang, T. Sunaba, Y. Sun, T. Shibata, K. Sasaki, H. Isoda, H. Kigoshi, and M. Kita

Acyl-CoA dehydrogenase long chain (ACADL) is a target protein of stylissatin A, an anti-inflammatory cyclic heptapeptide. 

J. Antibiot. 73, 589–592 (2020). 

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Reviews and Books

M. Kita

Structure analysis of marine natural products and their binding position analysis on the target molecules by using mass spectrometry. 

J. Synth. Org. Chem. Jpn. 76, 442–445 (2018). (in Japanese) 

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M. Kita

MyPR: Pursue an Interdisciplinary Natural Products Chemist. 

J. Synth. Org. Chem. Jpn. 77, 371–373 (2019). (in Japanese) 

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M. Kita and H. Kigoshi

Discovery and use of natural products and derivatives as chemical probes. 

in Discovery and Utility of Chemical Probes in Target Discovery, Ed. P. Brennan (The Royal Society of Chemistry), pp. 124–149 (2020).

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