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2021

For detail, see the link 

(Nagoya University

 Faculty Profile)

Original Papers

O. Kutomi, R. Yamamoto, K. Hirose, K. Mizuno, Y. Nakagiri, H. Imai, A. Noga, J. M. Obbineni, N. Zimmermann, M. Nakajima, D. Shibata, M. Shibata, K. Shiba, M. Kita, H. Kigoshi, Y. Tanaka, Y. Yamasaki, Y. Asahina, C. Song, M. Nomura, M. Nomura, A. Nakajima, M. Nakachi, L. Yamada, S. Nakazawa, H. Sawada, K. Murata, K. Mitsuoka, T. Ishikawa, K. Wakabayashi, T. Kon, and K. Inaba

A dynein-associated photoreceptor protein prevents ciliary acclimation to blue light.  

Sci. Adv. 7, eabf3621 (2021).

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Y. Araki, Y. Hanaki, M. Kita, K. Hayakawa, K. Irie, Y. Nokura, A. Nakazaki, and T. Nishikawa

Total synthesis and biological evaluation of oscillatoxin D, E, and F. 

Biosci. Biotech. Biochem. 85, 1371–1382 (2021). 

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[Link]

H. Hattori, T. Mori, T. Shibata, M. Kita, and T. Mitsunaga

6-Paradol acts as a potential anti-obesity vanilloid from Grains of Paradise. 

Mol. Nutr. Food Res. 2100185 (2021).

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D. H. Utomo, A. Fujieda, K. Tanaka, M, Takahashi, K. Futaki, K. Tanabe, H. Kigoshi, and M. Kita

The C29–C34 parts of antitumor macrolide aplyronine A serve as versatile actin-affinity tags.

Chem. Commun. 57, 10540–10543 (2021). 

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N. Hanif, D. Iswantini, Y. Hioki, A. Murni, M. Kita, and J. Tanaka

Flavokawains, plant-derived chalcones, inhibit differentiation of murine pre-adipocytes. 

Chem. Lett. 51, 54–57 (2022). 

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[Link]

T. Tsuda, A. Arai, and M. Kita

Ligand-dissociation-type N,N-dimethylaminopyrene probes for in situ site-specific protein labeling. 

Chem. Asian J. 17, e202200631 (2022). 

S. N. N. Makiyah, M. Kita, I. Setyawati, and S. Tasminatun

Dioscorea alata L. improves diabetes through anti-hyperglycemia, anti-inflammation, ameliorate insulin resistance and mitochondrial dysfunction. 

Indones. Biomed. J. 14, 365–375 (2022). 

T. T. H. Le, Y. Hioki, P. Wonganan, T.-K.-D. Le, V.-K. Nguyen, M. Kita, and W. Chavasiri

A new neolignan and a new phenolic acid from the heartwood of Mansonia gagei JR Drumm. 

Nat. Prod. Res. published online (2022). 

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D. H. Utomo and M. Kita

Binding mode of actin–aplyronine A–tubulin heterotrimeric complex revealed by molecular dynamics simulation

Bull. Chem. Soc. Jpn. 96, 120–126 (2023). 

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Y. Hioki, T. Sato, T. Iwao, J. Ikuma, A. Kawamura, T. Ohyoshi, Y. Tsunematsu, and M. Kita

Discovery of new cytotoxic aplaminone derivatives from the sea hare Aplysia kurodai and elucidation of their accumulation from local sea algae through the food chain.

Eur. J. Org. Chem. 26, e202300084 (2023). 

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M. Morishita, K. Hada, M. Kita, and T. Nishikawa

The asymmetric total synthesis and configuration confirmation of aplysiaenal and nhatrang A, truncated derivatives of aplysiatoxin and oscillatoxin.

J. Nat. Prod. 86, 1033–1041 (2023). 

Y. Yano, R. Fukuoka, A. D. Maturana, S. D. Ohdachi, and M. Kita

Mammalian neurotoxins, Blarina paralytic peptides, cause hyperpolarization of human T-type Ca channel hCav3.2 activation.

J. Biol. Chem. 299, 105066 (2023). 

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F. Nakashima, W. Qi Loh, M. Wakabayashi, S. Shimomura, H. Hattori, M. Kita, A. Inoue, K. Uchida, and T. Shibata

Eriodictyol and thymonin act as GPR35 agonists.

Biosci. Biotechnol. Biochem. in press (2023).

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M. Itakura, D. H. Utomo, and M. Kita

Development of actin dimerization inducers inspired by actin-depolymerizing macrolides.

Chem. Commun. 60, 4910–4913 (2024). 

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M. Nakatani, S. Ebihara, and M. Kita

Development of diazirine–alkyne tag for protein–ligand interaction analysis with photoaffinity labeling.

Chem. Lett. 53, upae142 (2024).

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Y. Sun, A. Dakiiwa, M. Zhang, T. Shibata, and M. Kita 

Inhibition of Lysosomal Cathepsin A and Neuraminidase 1 Interaction by Anti-obesity Cyclic Peptide.

Chem. Eur. J. 30, e202402049 (2024).  

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Books and Reviews

M. Kita 

Chemical biology studies on aplyronine A, a PPI-inducing antitumor macrolide from sea hare. 

in New Tide of Natural Product Chemistry, Eds. H. Ishikawa and H. Takayama (Springer Nature), pp. 59–75 (2023).

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