主な発表論文

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D. H. Utomo, A. Fujieda, K. Tanaka, M, Takahashi, K. Futaki, K. Tanabe, H. Kigoshi, and M. Kita

The C29–C34 parts of antitumor macrolide aplyronine A serve as versatile actin-affinity tags.

Chem. Commun. 57, 10540–10543 (2021). 

A. Arai, R. Watanabe, A. Hattori, K. Iio, Y. Hu, K. Yoneda, H. Kigoshi, and M. Kita

N,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis. 

Sci. Rep. 10, 7311 (2020). 

M. ZhangT. SunabaY. SunK. SasakiH. IsodaH. Kigoshi, and M. Kita

Anti-inflammatory marine cyclic peptide stylissatin A and its derivatives inhibit differentiation of murine preadipocytes. 

Chem. Commun. 55, 5471–5474 (2019). 

R. Watanabe, Y. Hu, K. Iio, K. Yoneda, A. Hattori, A. Arai, H. Kigoshi, and M. Kita

Specific protein-labeling and ligand-binding position analysis with amidopyrene probes as LDI MS tags. 

Org. Biomol. Chem. 16, 7883–7890 (2018). 

K. Yoneda, Y. Hu, R. Watanabe, M. Kita, and H. Kigoshi

Binding position analysis of target proteins with the use of amidopyrene probes as LA-LDI enhancing tags.

Org. Biomol. Chem. 14, 8564–8569 (2016). 

 

J. J. Sato, S. D. Ohdachi, L. M. Echenique–Diaz, R. Borroto–Páez, G. Begué–Quiala, J. L. Delgado–Labañino, J. Gámez–Díez, J. Alvarez–Lemus, S. T. Nguyen, N. Yamaguchi, and M. Kita

Molecular phylogenetic analysis of nuclear genes suggests a Cenozoic over-water dispersal origin for the Cuban solenodon.

Sci. Rep. 6, 31173 (2016).

 

K. Yoneda, Y. Hu, M. Kita, and H. Kigoshi

6-Amidopyrene as a label-assisted laser desorption/ionization (LALDI) enhancing tag: development of photoaffinity pyrene derivative. 

Sci. Rep. 5, 17853 (2015). 

M. Kita, H. Oka, A. Usui, T. Ishitsuka, Y. Mogi, H. Watanabe, M. Tsunoda, and H. Kigoshi

Total synthesis of mycalolides A and B through olefin metathesis.

Angew. Chem. Int. Ed. 54, 14174–14178 (2015).

A. Kawamura, M. Kita, and H. Kigoshi

Aplysiasecosterol A: a 9,11-secosteroid with an unprecedented tricyclic γ-diketone structure from the sea hare Aplysia kurodai.

Angew. Chem. Int. Ed. 54, 7073–7076 (2015).

 

M. Kita and H. Kigoshi

Marine natural products that regulate multiple cytoskeletal protein interactions.

Nat. Prod. Rep. 32, 534–542 (2015). 

 

M. Kita, Y. Hirayama, K. Yoneda, K. Yamagishi, T. Chinen, T. Usui, E. Sumiya, M. Uesugi, and H. Kigoshi

Inhibition of microtubule assembly by a complex of actin and antitumor macrolide aplyronine A.

J. Am. Chem. Soc. 135, 18089–18095 (2013). 

 

M. Kita, Y. Hirayama, K. Yamagishi, K. Yoneda, R. Fujisawa, and H. Kigoshi

Interactions of the antitumor macrolide aplyronine A with actin and actin-related proteins established by its versatile photoaffinity derivatives.

J. Am. Chem. Soc. 134, 20314–20317 (2012).

 

M. Kita, Y. Hirayama, M. Sugiyama, and H. Kigoshi

Development of highly cytotoxic and actin-depolymerizing biotin derivatives of aplyronine A, an antitumor macrolide of marine origin.

Angew. Chem. Int. Ed. 50, 9871–9874 (2011).

 

M. Kita, D. StC. Black, O. Ohno, K. Yamada, H. Kigoshi, and D. Uemura

Duck-billed platypus venom peptides induce Ca2+ influx in neuroblastoma cells.

J. Am. Chem. Soc. 131, 18038–18039 (2009).

J. Hao, F. Matsuura, Y. Kishi, M. Kita, D. Uemura, N. Asai, and T. Iwashita

Stereochemistry of pteriatoxins A, B, and C.

J. Am. Chem. Soc. 128, 7742–7743 (2006). 

 

M. Kita, Y. Nakamura, Y. Okumura, S. D. Ohdachi, Y. Oba, M. Yoshikuni, H. Kido, and D. Uemura

Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: isolation and characterization.

Proc. Natl. Acad. Sci. U.S.A. 101, 7542–7547 (2004). 

 

M. Kita, M. Kondo, T. Koyama, K. Yamada, T. Matsumoto, K. –H. Lee, J. –T. Woo, and D. Uemura

Symbioimine exhibiting inhibitory effect of osteoclast differentiation, from the symbiotic marine dinoflagellate Symbiodinium sp.

J. Am. Chem. Soc. 126, 4794–4795 (2004).